Notes on the 1918 Flu Pandemic and relationship to Swine Flu
Influenza A virus was first isolated by RE Shope* in 1931 from swine and by W. Smith, et al.**, in 1933 from humans, approximately 15 years after the 1918 “Spanish” flu world pandemic. Recently, RNA sequences of the 1918 virus have been studied by researchers at the Armed Forces Institute of Pathology (AFIP) in Maryland, which had stored specimens of 70 human autopsy cases of the 1918 flu pandemic.* In addition, influenza RNA was extracted from a preserved bird from the 1915-1918 era stored at the Smithsonian Institution. The work done confirms that the 1918 virus was an H1N1 virus and was closely related to swine and human H1N1 viruses that Swope isolated in the 1930s. However, both 1930 human and swine viruses were genetically distinct from the 1918-era archived wild bird virus from the Smithsonian. Hence, the researchers hypothesize that the virus causing the 1918 pandemic was unlikely transmitted directly from birds to humans or pigs. Rather, they think that the H1N1 pandemic virus likely circulated among swine and/or humans for some period, undergoing drift, before leading to widespread illness in 1918. Source:http://www.semp.us/publications/biot_reader.php?BiotID=162
video on World Health Global Influenza Surveillance Network
The Threat of Pandemic influenza
Are We Ready? (Free scientific lectures (2005) to download)
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Vivienne (not verified)
Tue, 2009-04-28 00:08
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We ultimately reap what we sow!
ferrand stobart (not verified)
Tue, 2009-04-28 02:00
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Swine 'flu - possible pandemic - useful resources
Sheila Newman
Thu, 2009-04-30 11:49
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Google map of swine flu cases
Anonymous (not verified)
Tue, 2009-05-19 08:21
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Swine Flu Symptoms
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