What do we know about Chloroquine use against COVID-19?
Chloroquine (and hydroxycloroquine) are related drugs that have been used for over 70 years to treat and prevent malaria. They have both antiviral and anti-inflammatory properties.
French studies
Professor Didier Raoult, who has a laboratory and hospital beds in Marseille, France, has been promoting chloroquine as an effective treatment for COVID-19 Coronavirus. From 16 March 2020 he trialed treatment of 24 COVID-19 patients with 600 mg of Chloroquine daily for 10 days.
He reported that six days later only 25% of these patients still carried the virus, whereas without chloroquine one would expect 90% to still be infected and infectious. The implication is that Chloroquin shortened the course of the illness.
The study may also have suggested that additional treatment with the antibiotic azithromycin led to better outcomes where secondary pneumonias of bacterial origin occurred.
Raoult has the qualifications to make serious claims in this field. He is a microbiologist specialising in infectious diseases and a professor in the Medical Faculty at the University of Aix-Marseilles. He is widely recognised for his work. Since 2008 he has been director of the URMITE Research Unit in infectious and tropical diseases.
Although the data are not yet published, the French Government is trying to reproduce the study.
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